The Genetics of Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic cause of chronic kidney disease, affecting approximately 1 in 1000 individuals worldwide. This accounts for up to 10% of all cases of end-stage renal disease (ESRD). “Autosomal dominant” means that both males and females are affected equally, and that

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